alternative_right shares a report from ScienceAlert: It might be reasonable to think that there's an indelible link between the heart and the body it resides in -- the processes that affect one inevitably affect the other. But a new preprint, uploaded to bioRxiv and yet to be peer-reviewed, suggests that this may only be true up to a point. Take the heart out of the body and put it in a new one, and something incredible happens. The transplanted heart begins to take on the biological age of its new owner. Older hearts transplanted into younger recipients appear to become biologically younger, while younger hearts placed in older bodies show signs of accelerated aging.

Read more of this story at Slashdot.

An estimated 2.3 million cancer cases worldwide in 2024, about one in eight, were attributable to infections, according to a study published in The Lancet Oncology. "This recent Lancet data is a profound reminder that a significant portion of our global cancer burden is fundamentally preventable," said David Greenberg, MD, of Hackensack Meridian Jersey Shore University Medical Center, in a news release. "We have historically siloed infectious diseases and oncology, but they are deeply intertwined. By shifting our focus toward aggressive infection control, we can literally vaccinate and treat our way out of millions of future cancer diagnoses." From a report: The study found that an estimated 2.3 million new cancer cases were attributable to infections globally in 2024, equivalent to 12% of all cancer cases. Of these, the largest number (760,000 cases, or 4%) were caused by H. pylori, followed by HPV (750,000 cases, or 4%), HBV (360,000 cases, or 2%), EBV (260,000 cases, or 1%) and HCV (160,000 cases). More than three quarters of infection-attributable cancers occurred in low- and middle-income countries. Eastern Asian had the largest burden, with 990,000 cases (42% of the global total). Rates were also higher than the global average in sub-Saharan Africa, Central and Eastern Europe and Southeast Asia.

Read more of this story at Slashdot.

alternative_right shares a report from Phys.org: Nanoparticles could someday provide a new way to help soldiers fight back against deadly nerve agents on the front lines. In a new study, Northwestern University scientists developed a nanoparticle-based compound that, when mixed into clothing dyes, could limit the impact of chemicals commonly found in pesticides, insecticides and nerve agents. Manufacturers could potentially add the nanoparticles to clothing used by those most at risk, such as farmers' masks and gloves or soldiers' uniforms and tactical gear. Or, if someone is exposed to a potentially deadly chemical, they could spray their clothing with water mixed with the compound to deactivate the chemical before its damaging effects take hold. The study has been published in the journal ACS Nano.

Read more of this story at Slashdot.

The Athletic reports that researchers at the University of Utah are studying itPBM, a medical-grade red-light therapy that has shown promising signs of reducing brain inflammation and improving cognition, mood, anxiety, motor performance and neural connectivity. The report centers in part on former BYU football star and University of Utah adjunct professor Larry Carr, who says the treatment helped him after years of brain damage from repeated head impacts. An anonymous reader shares an excerpt from the report: ... The knife, the call, the diagnosis in 2013, would lead [Carr] on a life-changing mission -- one in which he and a team of researchers at the University of Utah would eventually compile research that one of those researchers, Elisabeth Wilde, Ph.D, co-director of the Traumatic Brain Injury (TBI) and Concussion Center, calls "striking." The treatment they are studying is called photobiomodulation therapy, or itPBM (intranasal transcranial PBM), also known as red-light therapy. It is different from the kind of superficial red-light usage one can find on social media skincare channels or at a wellness boutique, and its application is broader. The research includes multiple studies, and is not just focused on ex-football players, but on women and men in various walks of life. The group recently published their latest results in the Journal of Neurotrauma, based on a study that followed 26 BYU football players throughout a season, suggesting the treatment could "potentially safeguard neurological health without reduced playing time or contact exposure." Definitive clinical trials haven't been run yet; broader research and validation is required, and some in the field are skeptical. Carr acknowledges some have told him that it could be "too good to be true." Still, other outside experts who spoke with The Athletic call the findings promising. They make sure to caution: This is not a cure-all, and there is much more to be tested. But the findings have been compelling enough to justify more research and more speculation. Researchers say 14 peer-reviewed studies have linked itPBM with improvements in cognition, mood, anxiety, attention, executive function, motor performance, and other measures, while brain imaging has shown reduced inflammation and improved connectivity. One of the most striking findings mentioned in the report came from a study of 26 BYU football players during the 2021 season. Players who did not receive treatment developed significant, widespread brain inflammation, while the treated group showed no comparable increase and even demonstrated reduced inflammation in some brain regions. As researcher Michael Carr put it, "I believe our BYU data suggests the players' brains using itPBM are actually healthier after the season." He added: "That is a first." Carr also said treated participants showed fewer symptoms of depression, anxiety, stress and PTSD, along with faster processing, better sustained attention and stronger executive function. Researchers have also observed improvements in balance, motor control and grip strength. Taken together, the findings suggest itPBM may have a neuroprotective effect.

Read more of this story at Slashdot.

A medical report published earlier this week says a boy in the U.K. developed erythema ab igne, or "toasted skin syndrome," after resting a laptop on his abdomen for up to eight hours a day, often while it was charging. "The marks were described as being in a patch about 15 centimeters (six inches) wide, made of flat, reddish-brown 'interlacing lines forming irregular circles and a lace-like morphology,'" reports Ars Technica. From the report: Based on the appearance, the doctors started reconsidering some sort of bruising and started asking him more questions. This is when he mentioned that he was homeschooled and used a laptop for his schoolwork. He said he typically did his work by resting his laptop on his abdomen while he worked, sometimes for up to eight hours a day, and often while the laptop was charging. Then they understood what it was. The doctors diagnosed the boy with erythema ab igne (EAI), which translates from Latin as "redness from fire" and is also sometimes called "toasted skin syndrome." This is a skin condition caused by repeated, prolonged exposure to low-grade heat -- heat not hot enough to cause actual burns. It's most often seen in adults, and common causes include using heating pads or hot water bottles for chronic pain or sitting too close to space heaters. Some people also develop it from certain occupational hazards, like glassblowing and metal work. EAI produces a lace-like rash, just like the boy's. It's unclear how EAI develops exactly. But researchers hypothesize that chronic heat exposure leads to damage to superficial blood vessels and the release of red blood cells, forming the tell-tale red reticulated pattern. While the boy's condition looked ominous, the good news is that EAI is generally benign and reversible -- once you remove the heat source. For severe or long-term conditions, some pigmentation and scarring can remain. But the boy's parents checked back in over several months, reporting that the rash faded and then completely resolved. Hopefully, he also got some sort of laptop stand.

Read more of this story at Slashdot.