An anonymous reader quotes a report from The Guardian: It is the bane of every fruit bowl: sliced banana that turns brown before it has reached the table. But such woes could soon be a thing of the past, with gene-edited bananas that keep their freshly peeled color now one step closer to reaching British shoppers. According to Tropic, the Norwich-based agricultural-biotechnology company that developed the fruit, the bananas have the same taste and texture but stay "fresh, yellow and appetizing long after peeling and slicing." Gilad Gershon, the chief executive of Tropic, said the flesh of the new banana resisted browning for an extra day or two -- and longer if chilled. He added that the innovation could make it easier to add bananas to prepackaged products such as fruit salads and breakfast pots, as well as reducing waste. [...] Tropic developed the bananas by using a gene-editing technology called Crispr-Cas9 to alter all three copies of a single gene within the fruit. As a result, they were able to reduce the production of polyphenol oxidase, an enzyme that causes browning. A similar approach has been effective in reducing browning in other produce, including mushrooms. Tropic said the non-browning bananas could reduce food waste and CO2-equivalent emissions along the supply chain by more than 25%. "This could support an annual reduction in CO2 emissions of over 9m tonnes in the banana export market alone," the company said. [...] Gershon said Tropic had gained regulatory approval for the non-browning bananas in 10 other countries including Japan, Brazil and the Philippines. The fruit is already being grown in Latin America.

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"New research led by Stanford Medicine reveals that what we call the brain is two distinct organs that evolved independently over hundreds of millions of years," Stanford Medicine announced this week: The new research finding shows that the human brain consists of two ancient nervous systems cleverly packaged together — a more primitive part that regulates our hearts' beating, our breathing and other functions, and another that makes us distinctly human, capable of poetry, mathematics and wondering about our own origins. The discovery could help explain why scientists have struggled for decades to grow certain types of brain cells in the laboratory — and it opens new avenues for studying devastating diseases that affect the brain stem... [S]cientists have struggled for decades to generate human hindbrain neurons in the laboratory. This gap has hampered research into devastating diseases affecting the brain stem, including spinal muscular atrophy and amyotrophic lateral sclerosis... The researchers' breakthrough came from studying the earliest moments of embryonic development... [Study co-authors Carolyn Dundes and Rayyan Jokhai] discovered that the hindbrain follows a separate developmental path, running in parallel to — rather than branching off from — the pathway that creates the forebrain and midbrain... This revelation explained decades of frustration in the field — scientists had been trying to turn one type of progenitor cell into another that it is fundamentally incapable of becoming... Armed with this knowledge, the researchers for the first time successfully coaxed human pluripotent stem cells (a kind of cell that can create any cell in the human body) to become functional hindbrain motor neurons in the laboratory... Finally, the researchers looked back over 550 million years of evolutionary time. They found the same two-origin brain pattern in chickens; zebrafish; and, remarkably, in acorn worms, tiny creatures living on the ocean floor that share a distant common ancestor with humans. Jellyfish, which diverged from humans about 600 to 700 million years ago, have two nervous systems at different ends of their body. "Our research suggests that evolution took two existing neural systems and pushed them together spatially," Loh said. "Having the brain as one organ would probably be more efficient, but we rely on this primordial way to make the brain as two separate pieces." Thanks to Slashdot reader Beeftopia for sharing the article.

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"Billionaire Bill Ackman's life was upended this February when his 26-year-old daughter collapsed in her Brooklyn apartment, suffering a brain hemorrhage that would render her unable to move, speak or see," writes the Washingon Post. But then... The hedge fund manager did what any good father would do — at least, any father with vast financial resources and what friends describe as a "Mr. Fix-It" tendency. He sprung into action, getting her topline care at New York City's Mt. Sinai Hospital and consulting a network of well-connected friends all over the world. He helped her access a novel cell therapy that has been gaining traction among longevity enthusiasts, who are seeking ways to prolong human life. And then — motivated by a newfound desire to accelerate scientific research — he vowed to spend more than $400 million to launch an institute dedicated to longevity and brain health... He posted this week that the U.S. Food and Drug Administration, in May, gave his daughter Lucy's medical team a first-time emergency authorization to transplant mitochondria — the energy-producing part of human cells — from her leg muscle to her eyes, in the hopes that the tiny cell powerhouses would facilitate healing in her optic nerves and perhaps even restore her vision. Ackman's story highlights the increasingly prominent role of the ultra-wealthy in making expensive medical bets on longevity treatments and other novel therapies, altering the direction of research as federal funding for science declines in the second Trump administration. But his saga is a deeply personal one, spurred by his daughter's medical crisis. The focus on longevity by Ackman, who made billions on Wall Street as a hedge fund manager, is aligned with similarly ambitious efforts from some of Silicon Valley's biggest names. OpenAI CEO Sam Altman has backed Retro Biosciences, a start-up whose goal is to add 10 healthy years to the human lifespan through cellular reprogramming. Amazon founder Jeff Bezos is reportedly a funder of Altos Labs, which focuses on cellular rejuvenation and resilience... Billionaire investor Peter Thiel, Google co-founder Sergey Brin and Oracle co-founder Larry Ellison are also deeply invested in life-extension methods and attempts to rewrite the biology of aging... The therapy given to Ackman's daughter Lucy, known as mitochondrial transplantation, is of great interest not only to people who have suffered injuries, but to longevity-focused scientists who believe that mitochondria may hold promise for reversing some of the effects of aging... In recent years, scientists have discovered that mitochondria have many other functions beyond converting food into energy. They serve as clearinghouses for damaged cells, opening up the possibility that they can help with cell regeneration and healing, said Daria Mochly-Rosen, professor of chemical and systems biology at the Stanford University School of Medicine and co-author of " The Life Machines: How Taking Care of Your Mitochondria Can Transform Your Health." "I am one of those who believes that focusing on mitochondrial health is a way to address many human diseases, including aging itself," she said. "It's exciting."

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